The medieval church is Grade II* Listed, and located within the Greatham Conservation Area.
In 1246, the church belonged to the heir of Roger Bertram, and was later granted, along with the manor, to the adjacent Greatham Hospital of St Mary and St Cuthbert. This has since been named the Hospital of God, and is now a nursing home. The church was erected over the foundations of an early Saxon building by Bishop Stichell of Durham in 1270. It was rebuilt in 1792, a clerestory added by the Reverend H B Tristram in 1869, and a new vestry and organ chamber added in 1881. The tower was built in 1909. The 4 bells were cast and installed by John Taylor & Co of Loughborough in 1931, and completely refurbished in 2020.